Bioinformatics
Transcriptomics
Transcriptomic analysis including differential expression analysis and metabolic pathways via GO enrichment
Providing comprehensive transcriptomic analysis services to explore gene expression and metabolic pathways. This service includes differential expression analysis to identify genes with significant changes in expression between conditions, as well as Gene Ontology (GO) enrichment analysis to uncover relevant biological processes and metabolic pathways. Advanced bioinformatics tools are used to analyse and interpret the data, offering insights into gene function, regulatory mechanisms, and cellular responses. Supporting research in genomics, molecular biology, and systems biology, this service enables a deeper understanding of the transcriptome and its role in health and disease.
Offering gene expression analysis services utilising microarrays, qPCR, and Nanostring technologies to study RNA and microRNAs. This service includes the extraction and quantification of RNA or microRNAs, followed by precise measurement of gene expression levels. Advanced analytical tools are employed to interpret the data, providing insights into gene regulation, cellular responses, and disease mechanisms. By leveraging these cutting-edge technologies, this service supports research in genomics, oncology, developmental biology, and more, enabling a deeper understanding of gene expression patterns and their biological implications
Supplying comprehensive single-cell RNA sequencing (RNAseq) analysis to explore gene expression at the individual cell level. This service includes detailed cell annotation to identify and classify distinct cell populations, as well as differential gene expression analysis to detect significant changes in gene activity between cell types or conditions. Advanced bioinformatics tools are employed to analyse the data, providing deep insights into cellular heterogeneity, developmental processes, and disease mechanisms. Supporting cutting-edge research in genomics, immunology, and developmental biology, this service enables a granular understanding of the transcriptome at single-cell resolution.
Metabolomics
Delivering metabolomics services to analyse and interpret the complete set of metabolites within biological samples. This service includes the extraction, identification, and quantification of metabolites using advanced techniques such as mass spectrometry and nuclear magnetic resonance (NMR). Detailed metabolic profiling and pathway analysis are performed to offer insights into biochemical processes and metabolic changes associated with health, disease, and treatment responses. Supporting research in systems biology, pharmacology, and clinical studies, these services enable a deeper understanding of metabolic networks and their role in physiological and pathological conditions
Genomics
Delivering whole genome analysis to study the resistance and virulence of pathogens such as Staphylococcus aureus, Mycobacterium tuberculosis, and Klebsiella pneumoniae. This service includes sequencing the complete genomes of these bacteria, identifying genetic mutations associated with antibiotic resistance and virulence factors. Advanced bioinformatics tools are used to analyse the genetic data, offering insights into the mechanisms driving resistance and pathogenicity. By leveraging cutting-edge genomic technologies, this service supports researchers and healthcare professionals in developing targeted treatment strategies, enhancing infection control measures, and improving patient outcomes
Providing viral mutation analysis to identify genetic variations and generate consensus sequences. This service includes sequencing viral genomes to detect mutations, track their evolution, and understand their implications for viral behavior and pathogenicity. Advanced bioinformatics tools are used to analyse the data and create consensus sequences that represent the most common viral genetic variants. Supporting research in virology, epidemiology, and vaccine development, this service offers valuable insights into viral mutations and their impact on transmission, immune evasion, and treatment efficacy
Microbiome
We provide comprehensive microbiome analysis by shotgun sequencing to investigate microbial communities at a detailed genomic level. This service includes full sequencing of microbial DNA in a sample, allowing for the identification and characterization of bacteria, viruses, fungi, and other microorganisms. Advanced bioinformatics tools are used to analyze the data, offering insights into alpha diversity (within-sample diversity) and beta diversity (between-sample diversity). This approach allows for a deeper understanding of microbial composition, functional potential, and interactions, supporting research in health, disease, environmental studies, and more.
Multiomics
We provide comprehensive multi-omics services that integrate different omics data, including genomics, transcriptomics, proteomics and metabolomics. This service combines advanced analytical techniques to offer a holistic view of biological systems, allowing the study of complex interactions and regulatory networks. By integrating different omics layers, insights are obtained into gene expression, protein function, metabolic pathways and cellular processes. We support research in personalized medicine, disease mechanisms and systems biology, facilitating a deeper understanding of biological complexity and promoting innovative solutions in health and disease.
Machine learning
Health
Premium Research utilises advanced predictive models to support disease diagnosis, foresee clinical outcomes, and personalise treatments. Our algorithms analyse large volumes of medical data to identify patterns and provide healthcare professionals with valuable tools to make more informed and precise decisions
Utilising predictive models to personalise treatments for chronic diseases such as diabetes and hypertension. By analysing individual patient data, these models can recommend specific adjustments in medication and lifestyle to maximise treatment efficacy. This service helps healthcare providers tailor interventions to each patient's unique needs, improving health outcomes and enhancing the overall effectiveness of chronic disease management.
Developing predictive models to identify patients at high risk of readmission. By analysing clinical and demographic data, these models assist healthcare professionals in implementing preventive interventions and personalised follow-up plans to reduce readmission rates. This service enhances patient care by enabling timely and targeted actions, ultimately improving health outcomes and reducing healthcare costs.
Developing algorithms to analyse clinical trial data and patient records to evaluate the efficacy and side effects of new medications. This service enables pharmaceutical companies and healthcare professionals to make informed decisions about the adoption of new treatments. By leveraging advanced analytics, the evaluation process ensures accurate assessment of therapeutic benefits and risks, supporting the development of safer and more effective medications.
Applying machine learning to analyse genomic sequences and identify genetic predispositions to diseases. This service facilitates the development of personalised genetic therapies and the implementation of preventive medicine programs based on the patient's genetic profile. By leveraging advanced analytics, genomic analysis provides insights into individual health risks, enabling tailored interventions and enhancing the effectiveness of healthcare strategies
Developing predictive models to manage and monitor chronic diseases by analysing patient data, including lifestyle habits and treatment adherence. This service helps physicians provide proactive and personalised care, improving the quality of life for patients. By leveraging data-driven insights, healthcare providers can tailor interventions to each patient's unique needs, enhancing disease management and patient outcomes.
Utilising machine learning algorithms to detect anomalies in medical images such as X-rays, MRIs, and CT scans. These systems can accurately identify lesions, tumors, and other conditions, enhancing the speed and precision of radiological diagnosis. This service supports healthcare professionals by providing reliable and efficient tools for early detection and accurate assessment of medical abnormalities, ultimately improving patient care outcomes.
Business & consumers
Premium Research applies Machine Learning algorithms, clustering techniques and pattern analysis to identify common behaviors among customers in order to divide them into homogeneous groups based on similar characteristics and behaviors. This allows for personalized marketing strategies, improved customer retention and increased effectiveness of promotional campaigns. Our approach helps businesses better understand their customers and respond to their specific needs.
This service enables businesses to segment their customer base more effectively and tailor their approaches to meet the specific needs and preferences of different groups, improving engagement and marketing effectiveness.
In industries such as telecommunications and subscription services, we can employ predictive models to identify customers who are most likely to churn. By anticipating these behaviors, companies can implement proactive measures to retain their customers and reduce cancellation rates, thereby improving customer satisfaction and financial stability.
We identify unusual patterns in business data using advanced analytics such as interquartile ranges. This solution is designed to optimize organizational management, detect inefficiencies and prevent risks, offering a practical and personalized approach to the business world.
We simulate business processes in virtual environments with digital twins. These replicas allow us to analyze, optimize and predict the behavior of complex systems, improving strategic decision-making and operational efficiency in any sector.
We develop personalized virtual agents that are disconnected from the Internet to ensure privacy. Connected only to internal databases, these chatbots help quickly access valuable information within the organization, improving productivity and security.
We design artificial intelligence algorithms tailored to the client's needs, operating completely offline to ensure maximum security and privacy. Ideal for projects requiring sensitive analysis or environments disconnected from the network.
We conduct detailed, customized analysis to understand market behavior and assess the impact of business or public policies. We use advanced data analytics and artificial intelligence tools to deliver actionable, informed reporting that guides strategic decision-making with precision and confidence.
Circular Economy
Developing predictive models to forecast the quantity and type of waste generated in different areas and at various times. This service can help authorities and companies better plan their collection and recycling capacities, minimising environmental impact. By leveraging advanced analytics, these models can provide accurate predictions that support efficient waste management strategies and sustainable environmental practices.
Implementing machine learning algorithms to optimise waste collection routes based on real-time data on container fill levels and waste generation patterns. This service can reduce operational costs and improves service efficiency. By leveraging advanced analytics, these algorithms can ensure that waste collection is timely and efficient, enhancing overall waste management and environmental sustainability.
Applying predictive models can enable to evaluate the environmental impact of products throughout their life cycle, from production to disposal. This service is able to allow companies to identify opportunities to enhance the sustainability of their products and processes. By leveraging advanced analytics, these assessments can provide insights into reducing environmental footprints and improving overall product sustainability, supporting more eco-friendly business practices.
Utilising predictive models capable to forecast the demand for recycled materials across different industries. This service can enable recyclers and material suppliers to adjust their production and supply to meet demand more efficiently. By leveraging advanced analytics, these predictions are able to help optimise resource allocation, enhance supply chain efficiency, and support sustainable practices in the recycling industry.
Biostatistics
Providing comprehensive shotgun microbiome analysis to investigate microbial communities at a detailed genomic level. This service includes whole-genome sequencing of all microbial DNA within a sample, allowing for the identification and characterisation of bacteria, viruses, fungi, and other microorganisms. Advanced bioinformatics tools are utilised to analyse the data, offering insights into alpha diversity (within-sample diversity) and beta diversity (between-sample diversity). This approach enables a deeper understanding of microbial composition, functional potential, and interactions, supporting research in health, disease, environmental studies, and more.
Delivering metabolomics services to analyse and interpret the complete set of metabolites within biological samples. This service includes the extraction, identification, and quantification of metabolites using advanced techniques such as mass spectrometry and nuclear magnetic resonance (NMR). Detailed metabolic profiling and pathway analysis are performed to offer insights into biochemical processes and metabolic changes associated with health, disease, and treatment responses. Supporting research in systems biology, pharmacology, and clinical studies, these services enable a deeper understanding of metabolic networks and their role in physiological and pathological conditions
Providing comprehensive multiomics services that integrate various omics data, including genomics, transcriptomics, proteomics, and metabolomics. This service combines advanced analytical techniques to offer a holistic view of biological systems, enabling the study of complex interactions and regulatory networks. By integrating different omics layers, insights into gene expression, protein function, metabolic pathways, and cellular processes are achieved. Supporting research in personalised medicine, disease mechanisms, and systems biology, these services facilitate a deeper understanding of biological complexity and drive innovative solutions in health and disease
Providing comprehensive multiomics services that integrate various omics data, including genomics, transcriptomics, proteomics, and metabolomics. This service combines advanced analytical techniques to offer a holistic view of biological systems, enabling the study of complex interactions and regulatory networks. By integrating different omics layers, insights into gene expression, protein function, metabolic pathways, and cellular processes are achieved. Supporting research in personalised medicine, disease mechanisms, and systems biology, these services facilitate a deeper understanding of biological complexity and drive innovative solutions in health and disease
Supplying comprehensive whole genome analysis of SARS-CoV-2 to support research and public health efforts. This service includes sequencing the entire genome of the virus, identifying mutations, and tracking variants. Advanced bioinformatics tools are utilised to analyse the genetic data, providing insights into the virus's evolution, transmission patterns, and potential impact on vaccine efficacy. By leveraging cutting-edge technologies, this service enables researchers and healthcare professionals to better understand the behavior of SARS-CoV-2, inform public health strategies, and contribute to the development of effective treatments and vaccines.
Lab Support
Protocols Design & Execution
Offering expert lab support in designing protocols for immunofluorescence and immunohistochemistry stainings. This service includes the development of detailed and optimised protocols tailored to specific research needs, ensuring accurate and reproducible results. By leveraging extensive expertise in stainning techniques, these protocols guide researchers through the entire process, from sample preparation to imaging and analysis, enhancing the quality and reliability of experimental outcomes.
Providing expert lab support in designing protocols for tissue processing. This service includes the development of detailed and optimised protocols to ensure precise and reproducible tissue preparation for various applications. By leveraging extensive expertise in tissue processing techniques, these protocols guide researchers through each step, from fixation and embedding to sectioning and staining, enhancing the quality and consistency of experimental outcomes.
Delivering expert lab support in designing protocols for flow cytometry. This service includes the development of detailed and optimised protocols to ensure accurate and reproducible flow cytometry results. Leveraging extensive expertise in flow cytometry techniques, these protocols guide researchers through the entire process, from selecting the best pannel, to sample preparation and staining, data acquisition and analysis, enhancing the reliability and precision of experimental outcomes.
This service includes the execution of multi-analyte immunoassays (ELISA type), in which a wide range of biomarkers are analyzed in each sample to use the minimum possible volume and reduce process times and costs. We also offer advice on choosing the most suitable product and developing the protocol.
In vivo Procedures
Supplying expert lab support in animal surgery and the generation of animal models. This service includes the design and execution of surgical procedures and the development of specific animal models for research purposes. By leveraging extensive expertise in veterinary techniques and animal care, these services ensure precise, ethical, and reproducible outcomes, supporting advanced biomedical research and the study of disease mechanisms, therapeutic interventions, and drug efficacy.
Providing expert lab support in animal surgery and sample processing. This service includes the design and execution of surgical procedures, followed by the precise processing of biological samples. Leveraging extensive expertise in surgical techniques and sample handling, these protocols ensure accurate, ethical, and reproducible outcomes. This support is essential for advanced biomedical research, enabling the study of disease mechanisms, therapeutic interventions, and comprehensive data analysis.
Support & training in the framework of the following techniques, among others: tail blood extraction, surgery, nephrectomy, drug injection by tail or intraperitoneally, catheter implantation, blood extraction by cardiac puncture. These techniques can be applied both in SPF zone and biosafety level 2 in mice.
Cell Culture
Offering expert lab support in cell culture techniques. This service includes the support to establish, maintain, and optimise cell cultures for various research applications. Leveraging extensive expertise in cell culture methodologies, this support ensures the growth of healthy and contaminant-free cell lines. This service is essential for a wide range of biomedical research, including drug testing, genetic studies, and cellular biology, ensuring reliable and reproducible experimental outcomes.
Lab Strategic Planning
Delivering expert laboratory support in strategic planning for research on fibrosis and its connection with inflammation. Our services include the development and optimisation of laboratory protocols, resource allocation, and workflow design, specifically tailored to studies on fibrosis and related diseases. We offer our expertise in cellular and molecular mechanisms that regulate both fibrotic and inflammatory processes, as well as associated laboratory techniques. Essential for advancing research and therapeutic development, our support facilitates the research on fibrotic processes, treatment efficacy, and innovative therapeutic interventions.
Supplying expert lab support in strategic planning for angiogenesis research. This service includes the development and optimisation of lab protocols, resource allocation, and workflow design tailored to angiogenesis studies. Leveraging extensive expertise in angiogenesis research and lab management, this service ensures efficient, accurate, and reproducible outcomes. Essential for advancing research and therapeutic development, it supports the study of angiogenesis mechanisms, treatment efficacy, and innovative interventions.
Providing specialised laboratory support in strategic planning for research on inflammation. Our services encompass the development and optimisation of laboratory protocols, resource allocation, and workflow design, specifically tailored to studies on inflammation and associated conditions. With extensive expertise in cellular and molecular mechanisms that regulate inflammatory processes and associated laboratory techniques, we ensure efficient, accurate, and reproducible results. Essential for advancing research and therapeutic development, our support facilitates the study of inflammatory mechanisms, treatment efficacy, and innovative interventions for related diseases.
Providing comprehensive lab support services in strategic planning for peritoneal dialysis research and laboratory procedures. This service includes developing and optimising lab protocols, resource allocation, and workflow design tailored to peritoneal dialysis studies. Leveraging extensive expertise in dialysis techniques, clinical and preclinical research, this service ensures efficient, accurate, and reproducible outcomes. Essential for advancing research and clinical applications, it supports the study of dialysis efficacy, patient outcomes, and innovative therapeutic approaches.
Scientific Production & Communication
Bibliography
Offering expert support in the creation and management of bibliographies for scientific research. This service includes the compilation, organisation, and formatting of references according to specific citation styles. Leveraging extensive expertise in scientific literature and reference management tools, this service ensures that bibliographies are comprehensive, accurate, and professionally presented. Essential for researchers and academic writers, it enhances the credibility and rigor of scientific publications, theses, and grant applications.
Scientific Writing
Providing expert support in the writing of scientific review articles. This service includes comprehensive literature review, synthesis of current research, and clear presentation of findings and insights on specific topics. Leveraging extensive expertise in scientific writing and subject matter, this service ensures that review articles are thorough, well-structured, and professionally written. Essential for researchers and academics, these articles contribute to the body of scientific knowledge, support grant applications, and enhance academic reputation.
Offering comprehensive support in the writing of original scientific articles. This service includes the development, structuring, and writing of articles that present new research findings. Leveraging extensive expertise in scientific writing and research methodologies, this service ensures that articles are clear, accurate, and professionally presented. Essential for researchers and academics, these original articles contribute to scientific advancement, support grant applications, and enhance academic and professional recognition.
Delivering expert services in the writing of scientific book chapters. This service includes the development, structuring, and writing of comprehensive chapters that present in-depth research and insights on specific topics. Leveraging extensive expertise in scientific writing and subject matter, this service ensures that book chapters are detailed, accurate, and professionally presented. Essential for researchers and academics, these contributions enhance the body of scientific literature, support educational efforts, and strengthen academic and professional credentials.
Providing expert services in the writing of scientific abstracts. This service includes the concise summarisation of research findings, key insights, and implications in a clear and engaging manner. Leveraging extensive expertise in scientific writing, this service ensures that abstracts effectively capture the essence of the research while adhering to formatting and length requirements. Essential for researchers and academics, these abstracts enhance the visibility and impact of scientific presentations, publications, and grant applications.
Offering expert support in the writing of scientific meta-analyses. This service includes the comprehensive synthesis and analysis of data from multiple studies to derive robust conclusions. Leveraging extensive expertise in statistical methods and scientific writing, this service ensures that meta-analyses are thorough, accurate, and professionally presented. Essential for researchers and academics, these meta-analyses contribute to evidence-based practice, support grant applications, and enhance the credibility and impact of scientific research.
Providing expert services in the creation of scientific figures. This service includes the design and development of clear, accurate, and visually engaging figures to effectively present research data and findings. Leveraging extensive expertise in data visualisation and scientific communication, this service ensures that figures enhance the understanding and impact of scientific articles, presentations, and publications. Essential for researchers and academics, these figures support the clear communication of complex information and contribute to the overall quality and professionalism of scientific outputs.
Delivering comprehensive support in scientific reading and assessment. This service includes thorough review and critical evaluation of scientific literature to assess the quality, relevance, and impact of research findings. Leveraging extensive expertise in various scientific fields, this service ensures accurate interpretation and insightful analysis of existing studies. Essential for researchers, academic institutions, and industry professionals, it aids in literature reviews, evidence synthesis, and the identification of research gaps and opportunities.
Providing comprehensive support in the creation of scientific reports. This service includes the development, writing, and editing of detailed scientific documents that effectively communicate research findings. Leveraging extensive expertise in scientific writing and data analysis, this service ensures that reports are accurate, clear, and professionally presented. Essential for researchers and institutions, these reports enhance the dissemination of knowledge, support grant applications, and contribute to academic and clinical advancements.
Professional accreditation
Scientific Communication
Supplying expert support in the creation of scientific posters for conferences. This service includes designing and producing visually appealing and informative posters that effectively communicate research findings. Leveraging extensive expertise in scientific communication and design, this service ensures that posters are clear, engaging, and professionally presented. Essential for enhancing visibility and impact at conferences, these posters support the dissemination of research, facilitate knowledge exchange, and promote academic and professional recognition.
Supplying professional support in organising scientific events to facilitate knowledge sharing and collaboration. This service includes planning and executing conferences, workshops, symposia, and seminars that bring together researchers, academics, and industry professionals. Leveraging extensive experience in event management and scientific communication, this service ensures that events are well-coordinated, engaging, and impactful. Essential for advancing scientific discourse and fostering networking opportunities, the organisation of scientific events enhances the dissemination of research findings and promotes innovation within the scientific community.
Offering expert support in the creation of scientific dissemination materials. This service includes designing and producing a wide range of materials such as brochures, reports, infographics, videos, and digital content to effectively communicate research findings and insights. Leveraging extensive expertise in scientific communication and design, this service ensures that materials are clear, engaging, and professionally presented. Essential for enhancing the visibility and impact of scientific research, these dissemination materials support outreach efforts, promote knowledge exchange, and engage stakeholders across various platforms.
Providing professional servides to produce scientific videos to effectively communicate research findings and insights. This service includes scripting, recording, editing, and publishing high-quality video content that engages and informs the scientific community and the public. Leveraging extensive expertise in scientific communication and video production, this service ensures that videos are clear, engaging, and professionally presented. Essential for enhancing the reach and impact of scientific research, these videos support knowledge dissemination, promote public engagement, and foster a deeper understanding of complex scientific topics.